IMPLANTABLE SENSORS OFFER DATA-DRIVEN TELEMEDICINE FOR VULNERABLE POPULATIONS IN AN ERA OF COVID19
Injectsense in-vivo sensors aim to keep patients out of clinics while helping physicians improve quality of care
EMERYVILLE, Calif., April 21, 2020 – Americans spend 2.4 billion hours on doctor visits. This means that in normal times, thousands of patients a month go to a doctor’s office for routine evaluation of chronic conditions that could easily be monitored through sensor-enabled digital health. In times such as these, where the novel coronavirus requires all medical staff on deck, remote monitoring via implantable sensors can perform double duty and help save lives.
First, it can provide a telemedicine solution that keeps non-urgent but vulnerable populations out of clinics and emergency wards to make room for priority cases. Second, compared to periodic office visits, it offers a superior solution for managing therapy effectiveness, as well as the opportunity to reduce costs. Equally important, sensor-enabled digital health opens a new era of telemedicine, where physician access to continuous diagnostic data will add clinically actionable information to routine virtual health appointments.
Sensor-enabled digital health solutions: how they work
By periodically uploading continuous data to the cloud, implantable sensors offer a reimbursable, data-driven solution that may improve outcomes, providing an unprecedented window on fluctuation of chronic disease indicators and risk factors. Physicians will be able to easily mine data, receive alerts on priority patients, understand how to optimize dosage, and identify drug interference. Ultimately, they will have the capability to monitor multiple parameters at once for greater disease insight.
As an example of such a system, Injectsense has developed a miniature implantable sensor smaller than a grain of rice for continuous data monitoring. It can be injected or implanted in the doctor’s office, and measures different parameters, including pressure, temperature, body position, motion, and other variables that provide information on chronic disease.
Injectsense’s first application is measurement of intraocular pressure (IOP), a glaucoma progression risk indicator. The IOP sensors, which have been tested in live animals, periodically send data to the cloud, providing physicians with clinically actionable information, keeping typically vulnerable glaucoma patients out of the doctor’s office for routine IOP evaluations. The company’s strategic partner and major investor saw the advantages of the system early on for use in the monitoring of glaucoma patients.
“It’s extremely difficult to know how IOP fluctuates from hour to hour,” said Iqbal “Ike” Ahmed, MD, FRCSC, research director and professor at the Kensington Eye Institute of the University of Toronto. “The ability to see what’s actually going on during a 24-hour cycle for an individual patient’s IOP will contribute enormously to therapy effectiveness.”
Telemedicine Benefits of Sensor-Enabled Digital Health during a Pandemic
“The availability of a sensor-based monitor would make following a patient’s glaucoma much more complete,” said Jason Bacharach, MD, FAAO, founding partner and medical and research director at North Bay Eye Associates. “A clinician would be able to visualize a 24-hour IOP curve and identify peaks and the ability to assess for disease stability as well as therapeutic effectiveness would be enhanced. We could do this remotely, reducing the need for in-person visits, which would be particularly beneficial during stay-at-home orders with the COVID-19 pandemic.”
“When we developed the idea for this injectable platform six years ago, we saw it as essential to reducing the cost of unnecessary office visits across multiple medical domains -- ophthalmology, neurosurgery and other fields,” said Ariel Cao, CEO and president, Injectsense Inc. “Now the system can offer a highly viable approach to keeping physicians, clinics and hospitals available for priority patients during a time of need, while still providing doctors with a means to measure therapy effectiveness and receive reimbursement.”
Bringing Sensor-Enabled Health to Market for Maximum Value
The company is now heavily investing in a safe and effective sensor injection system as it moves towards first-in-human studies. Injectsense is targeting an accelerated path to market with support from its own strategic partners and investors in order to bring to market a solution that can protect the most vulnerable in today’s new reality.
INJECTSENSE DEMONSTRATES ANIMAL TO CLOUD IOP SENSING PATHWAY
Injectable Pressure Sensor Offers Platform for Multiple Medical Domains
San Francisco, October 9, 2019, AAO – Injectsense, a sensor-enabled digital health company, today announced completion of a successful in-vivo animal study of the first implantable sensor and monitoring system designed to collect long-term intraocular pressure (IOP) data. The Injectsense IOP-Connect system creates an organ-to-cloud data connection that enables the clinician to assess glaucoma therapy effectiveness at any time. The system is expected to provide unprecedented visibility into the IOP profile of the patient over time, and into previously unobserved changes that may affect glaucoma progression.
As part of the study, researchers at an accredited US research organization were able to implant the self-anchoring sensor safely and collect accurate pressure readings – in agreement with tonometry measurements – for the week-long test period. No device-related adverse events were reported.
“One of the challenges in addressing glaucoma is the lack of visibility into continuous IOP changes,” said Dr. Myron Yanoff, MD, FAAO, Chair Emeritus, Department of Ophthalmology at Drexel University and Adjunct Professor, Department of Ophthalmology at the University of Pennsylvania. “The product being developed by Injectsense is a game changer in how and when to regulate the treatment of glaucoma. It offers a tangible path to clinically actionable information, enabling new insights into the true relationship between IOP, glaucoma, and therapy effectiveness. It also opens a world of possibilities into basic research on the inherent changes in the mechanisms of glaucoma.”
Beyond ophthalmology, the sensor-enabled digital health platform is highly versatile, potentially enabling diagnostic and therapeutic applications in many different domains, from intracranial, urological, and various cardiovascular pressure parameters to neurosurgery and fluidic applications.
Injectsense is a sensor-enabled digital health company that enables tracking of progressive disease indicators and assessment of therapy effectiveness. It provides continuous, clinically actionable information through an injectable ultra-miniature sensor coupled with a secure digital health platform. Injectsense received Series B funding in April 2019 and is expecting to close a Series C round by year end. The company's Silicon Valley and Twin Cities product teams combine cutting-edge advances in microelectronics with best-in-class medical device development and expertise. The device is currently for clinical investigation only and is not commercially available. For more information regarding Injectsense’s business, visit injectsense.com.
INJECTSENSE ADDS EXPERTS TO MEDICAL ADVISORY BOARD
EMERYVILLE, Calif., March 2, 2017 – Injectsense, Inc. an innovative medical device firm that develops sensor-enabled digital health systems to measure therapy effectiveness, announced today additional members of its medical advisory board. The board, which includes world renowned specialists and surgeons in the ophthalmic field, provides valuable feedback on device requirements, procedures, risk mitigation, and regulatory issues. Ophthalmology is the company's initial market.
New members of the medical advisory board include Richard Lindstrom, M.D., founding member and attending surgeon at Minnesota Eye Consultants; and Kuldev Singh, M.D., Professor of Ophthalmology and Director of the Glaucoma Service at Stanford University, who serves on the FDA Advisory Committee for Ophthalmic Devices. Other members of the medical advisory board include Dr. Myron Yanoff, M.D., author or co-author of 30 textbooks on ophthalmology including the standard textbook Ophthalmology; Dr. Arthur Sit, Associate Professor and Vice Chair of Ophthalmology at the Mayo Clinic; Dr. Iqbal "Ike" Ahmed, M.D., who developed the field of micro-invasive glaucoma surgery (MIGS); Dr. Ernesto Collazo, a leader in laser eye surgery and advanced technology in healthcare; Dr. Jason Bacharach, founder and director of research at North Bay Eye Associates, specializing in pharmaceutical and device studies; Dr. Stephen Sinclair, owner and director of Sinclair Retinal Associates and adjunct professor at the Drexel University School of Medicine; and Dr. William Daney, a clinical emergency medicine specialist, medical director and instructor, with a focus on cardiology.
"We are extremely fortunate to have secured the commitment and ongoing strategic feedback from highly recognized medical professionals who understand the urgent need for continuous monitoring and clinically actionable information," said Ariel Cao, CEO and president, Injectsense, Inc. "This continuous data, when filtered, will enable earlier treatment for progressive disease."
CAUTION - Investigational Device. Limited by Federal law to investigational use.